Effect of lignocaine, sodium cromoglycate, and ipratropium bromide in exercise-induced asthma
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چکیده
منابع مشابه
Effect of lignocaine, sodium cromoglycate, and ipratropium bromide in exercise-induced asthma.
ABSTRACr Eight patients with exercise-induced asthma participated in a single-blind trial comparing the protective effects of inhaled lignocaine (estimated dose 48 mg), sodium cromoglycate (estimated dose 12 mg), and ipratropium bromide (estimated dose 120 ,g). Saline was used as control. Effects were assessed from the mean maximal percentage fall in forced expiratory volume in one second (FEVI...
متن کاملSodium cromoglycate and ipratropium bromide in exercise-induced asthma.
In thirteen patients with extrinsic asthma the effects of placebo, sodium cromoglycate, ipratropium bromide, and ipratropium bromide plus sodium cromoglycate were studied in a random double-blind fashion to assess their inhibitory action in exercise-induced asthma (EIA). Exercise testing consisted of steady state running on an inclined treadmill for up to eight minutes. In eight of the 13 patie...
متن کاملEffect of ipratropium bromide and/or sodium cromoglycate pretreatment on water-induced bronchoconstriction in asthma.
The mechanisms underlying water-induced bronchoconstriction are still not fully understood. Cholinergic reflexes and mast cell mediator release are currently believed to play an important pathogenetic role. In order to evaluate the relative contribution of each of these mechanisms, we studied the effect of ipratropium bromide (80 micrograms), a muscarinic antagonist, and sodium cromoglycate (20...
متن کاملDose-response study of sodium cromoglycate in exercise-induced asthma.
Ten patients with exercise-induced asthma participated in a single-blind dose-response study comparing the protective effect of inhaled sodium cromoglycate in increasing concentrations from 2 to 40 mg/ml. Saline was used as a control. Effects were assessed from the mean maximal percentage fall in forced expiratory volume in one second (FEV1) after the patients had run on a treadmill for eight m...
متن کاملNebulised ipratropium bromide and sodium cromoglycate in the first two years of life.
In a double blind crossover trial, we compared sodium cromoglycate, ipratropium bromide, and water in 23 asthmatic children less than 2 years old (mean age 11.8 months). Each child received nebulised solutions containing 20 mg of sodium cromoglycate, 250 micrograms of ipratropium bromide, or 2 ml water three times a day for three two month periods. Daily symptom scores did not show significant ...
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ژورنال
عنوان ژورنال: Thorax
سال: 1982
ISSN: 0040-6376
DOI: 10.1136/thx.37.10.737